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Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

Walter White, a New Mexico chemistry teacher, is diagnosed with Stage III cancer and given a prognosis of only two years left to live. He becomes filled with a sense of fearlessness and an unrelenting desire to secure his family's financial future at any cost as he enters the dangerous world of drugs and crime.

A modern update finds the famous sleuth and his doctor partner solving crime in 21st century London.

In a 1950s orphanage, a young girl reveals an astonishing talent for chess and begins an unlikely journey to stardom while grappling with addiction.