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Yu Takanashi, a former surgeon, joins the Comprehensive Diagnosis Department at Tenikai General Hospital, where he works alongside the brilliant yet eccentric Takao Ameku to solve mysterious medical cases.

Two fans of pop idol Ai are reincarnated as her "secret" baby twins, Aqua and Ruby, and grow up supporting her until the tragic day she is stabbed by a stalker. Flash forward a few years later, and Aqua and Ruby are high-school students determined to make it on their own in the cut-throat world of entertainment for personal reasons.

This is a medical manga set in a child psychiatry clinic, where the heroine, Shiho Tono, a trainee doctor, meets children with various mental illnesses, including the director Takashi Sayama, and tries to find solutions. There are very few stories that can be completed in one episode, and the style is often of dividing a theme into multiple stories and solving the problem from various angles, rather than solving the problem completely.

The day before Tomoki’s wedding day, he is falsely accused of sexual harassment. Due to the false accusation, he loses his job and his fiance leaves him. Tomoki decides to kill himself. While standing on the ledge of a rooftop building, he sees a woman running toward him and screaming. She is attacked by a man with a knife. Tomoki becomes involved and gets stabbed by the man, but it turns out the attack was a staged event and Tomoki was not really stabbed. Tomoki learns that the staged event is called "enijya," which takes place upon a client's request. This is the first time he hears of eniya. Tomoki decides to hire Aika to take revenge on people who falsely accused him of sexual harassment.
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