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In 1993, the Search for Extra Terrestrial Intelligence Project receives a transmission detailing an alien DNA structure, along with instructions on how to splice it with human DNA. The result is Sil, a sensual but deadly creature who can change from a beautiful woman to an armour-plated killing machine in the blink of an eye.

Trevor is a busboy who is so terrified of women that he takes in a young man addicted to heroin and then uses the drug to manipulate, coerce, and terrorize him into becoming "Dorothy", his twisted concept of the "ideal girlfriend."