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Based on the true life experiences of poet Jimmy Santiago Baca, the film focuses on half-brothers Paco and Cruz, and their bi-racial cousin Miklo. It opens in 1972, as the three are members of an East L.A. gang known as the "Vatos Locos", and the story focuses on how a violent crime and the influence of narcotics alter their lives. Miklo is incarcerated and sent to San Quentin, where he makes a "home" for himself. Cruz becomes an exceptional artist, but a heroin addiction overcomes him with tragic results. Paco becomes a cop and an enemy to his "carnal", Miklo.

Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.

Mac, the two-fisted, savvy cop finds that he's being saddled with a new partner, a known burnout, to work with him on a new and difficult case. The new partner is Ellis, an amazing detective, one who puts Sherlock Holmes to shame with his lightning-fast deductions. But he keeps assuming the personalities of entire casts of Television shows. This can be a problem when people begin shooting at them.

An uptight New York tax lawyer gets his life turned upside down, all in a single day, when he's asked to escort a feisty and free-spirited female ex-convict whom asks him to help prove her innocence of her crime.

While Popeye Doyle is investigating what appears to be a very simple drug overdose, he becomes involved in international intrigue. The Mosad and various other foreign diplomatic figures turn up everywhere he goes. The drug overdose becomes a very involved murder case.

When the Muppets graduate from Danhurst College, they take their song-filled senior revue to New York City, only to learn that it isn't easy to find a producer who's willing to back a show starring a frog and a pig. Of course, Kermit the Frog and Miss Piggy won't take no for an answer, launching a search for someone to take them to Broadway.
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