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In 1967, experimental filmmaker Jorgen Leth created a striking short film, The Perfect Human, starring a man and women sitting in a box while a narrator poses questions about their relationship and humanity. Years later, Danish director Lars von Trier made a deal with Leth to remake his film five times, each under a different set of circumstances and with von Trier's strictly prescribed rules. As Leth completes each challenge, von Trier creates increasingly further elaborate stipulations.

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The mutant fetus is born. Dr. Helmer comes under heavy scrutiny for a botched operation that left a patient braindead, and begins to dabble in the dark arts in order to ward off those seeking an end to his career. Hypochondriac Mrs. Drusse finally does have something bad happen to her medically when an ambulance hits her.

The waitresses at a Copenhagen bar find themselves listening to and advising various clients who wander in to unburden their current problems. The Blue Monk is so named because its jukebox constantly plays music by jazz musician Thelonius Monk. ...The Blue Monk

At The Kingdom, Denmark's most technologically advanced hospital, a number of strange and otherworldly events begin occurring, much to the dismay of its doctors and patients. A ghostly ambulance appears and disappears, the voice of a little girl calls to a patient in an elevator shaft, and a doctor's fetus begins growing at an alarming rate.

Jan thinks he is Swedish-Danish, but after his mother's death he discovers he was adopted. As his world begins to fall apart, he decides to find his birth parents. The hunt leads him to Portugal - in a taxi - where more surprises await him.

Four parallel stories about a Russian and his daughter trying to get to his wife's Russian Pizza House in New York, but they are stranded in Copenhagen. A girl getting married. A man finding his brother and starting a new life in the city. Two men working at a bridge. And it's all happening the same night.

Line married early to a crazy but lovely painter, who unfortunately one day became so crazy that he had to be hospitalized. For her, there was only one thing to do: refuse to let it get her down, quickly find a job—as a cashier at the local supermarket—set up a new home for her four children, and make it all work. But what about her dreams and love—and making ends meet...

After librarian Isolde attempts suicide, she leaves her politician husband for a younger student with a dark past. Isolde's former husband, however, has something else in mind for the young man.

Poet-filmmaker Jørgen Leth taps his own earliest inspirational veins by free-floating through a camera/microscope-enhanced set of poems with love as their first and final subject. For example, how a tropical island woman prepares for a meeting with her lover. The film was shot partly in the South Pacific with more than a nod to social anthropoliogist B. Malinowski's historical work The Sexual Life of Savages.
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