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Unable to support her second child, a boy, Alice Baldwin gives him up to the wife of Edward Stevens, a wealthy manufacturer. Her other child, a daughter, grows up, marries, and selfishly neglects her mother. Twenty years pass, and Alice's son, Edward, Jr., wins a place in the Stevens piano factory and falls in love with Julia Brennon, the owner's daughter. Meanwhile, the mother leaves home when her son-in-law objects to her presence, and she is rescued from a suicide attempt by Edward and Julia. At his foster father's home he realizes her identity, and at last they find happiness together.

A scientist discovers a death ray and locks it in a box, giving the key to his daughter, who soon finds herself hunted by criminals looking to steal the deadly mineral.

Richard Randall, a patriotic young lawyer speaks out against food profiteers. When ruthless food combine head, Everett Dearing, blackmails society idler Tony Terle into compromising Randall's wife, Beverly in an attempt to stop Randall's anti-war crusades. Ultimately, Terle is caught and confesses to killing Dearing, leading to Randall and Beverly's reunion.

Adapted from a novel by Larry Evans, Once to Every Man tells the tales of Danny Bolton, a pugnacious, hard-drinking country boy.

After a brief and unhappy marriage, Gladys Dale finds work as the companion to Diana Dorset, the daughter of a society matron. Mrs. Dorset also has a spendthrift son, Robert, who makes a number of unwelcome advances to Gladys. However, with the arrival of Edwin Fairfax, Mrs. Dorset's younger brother, Gladys finds a soul mate. But then Fairfax has to report for duty in France (being as World War I is going on) and he leaves.

Janet Rigsby loves Richard Morgan, a Denver college student, but loses him when he is caught in a fire. Shortly after Richard's presumed demise, Janet leaves her home and bears a son out of wedlock. Over the years, she struggles to make ends meet while raising Bud, her son, on her own. Although her savings are small, Janet manages to send Bud to college. Chastised for his poverty and illegitimate birth, Bud, who is in love with the college gardener's daughter, suffers the ridicule of his peers and eventually comes to blows with and threatens one particular boy for insulting his mother. In the ensuing confrontation, the boy is killed and Bud is arrested for the crime. During the course of the trial, Bud discovers that the district attorney is Richard Morgan, his father. The testimony of one expert witness reveals how the murder in truth was committed, and a liberated Bud happily reunites with his mother and new-found father.

Arnold L'Hommedieu and his friends Archie Hartogensis and Hugo Waldemar go to New York to find work after being unfairly expelled from college. Arnold starts off as helpful and idealistic, but after being beaten down by life, he decides he is only after money and becomes an opium smuggler. His pals have fared no better: Archie becomes a drug addict and is in debt thanks to his spendthrift fiancee, while Hugo has lost his money after investing in a show that flopped. The two go to Arnold for financial aid. They await a shipment of opium, but the police are onto them and raid the hideout; only Arnold evades the cops.

Ne'er-do-well Joe Louden scandalizes his small town and especially the proper Judge Pike. But through the love of young Ariel Taber, Joe shows the town who the real scoundrel is.

Jack Brookfield, a gambler with clairvoyant and hypnotic powers, is able to win at cards through his unique gift. But when he inadvertently hypnotizes young Clay Thorne, Thorne kills an enemy of Brookfield's while under a trance. No one believes Brookfield's protestations that Thorne is innocent of any murderous intent

Claire Martin, niece of the wealthy Mrs. Taylor, suffers from loss of memory. Under the effect of this, Claire acts as an entirely different person. She wanders through the woods seeking shelter and food, and finally reaches a cabin temporarily occupied by a New York sportsman, who is fishing and hunting in the woods.
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