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Confronted with his mother's infidelity and his father's emotional absence, João arrives at a sunset where he refuses to return home.

Egas Moniz, a man marked by perseverance and ambition. Audacious and in dissonance with a country full of “narrow-minded” people, Egas Moniz faced everyone so as to impose his scientific ideas, for which he was awarded, at a quite advanced stage of his life, the much-desired Nobel Prize for Medicine in 1949.

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Edward, a young expat gay man, finds himself caged in a glass box, after being abducted by the least person he could ever imagine: his own sister Helen. In order to be freed, he will need to be able to trick Helen, a deeply disturbed yet cunning woman, willing to go to great lengths to cure the young man from his birth nature.
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