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Three entwined stories of love, lust, danger and revenge.

An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.

Rescuers try to reach plane crash victims that are trapped on an isolated Mexican island populated by mutant baboons. Ron Perlman stars as a troubled guide hired to lead the mission.

Major Murphy, a US Army Investigator, has received a new assignment. Sgt. Gammon is suspected of dealing cocaine from his base, and Murphy must gather enough evidence to shut down Gammon and his entire operation. Along with his partner, Lt. Andrews, the Major goes undercover to infiltrate the gang and find out just how far up the chain of command these activities are going.

Pittsburgh cop Mike Justus is kicked off the force and moves away to relax in sunny Los Angeles. Unfortunately his dream retirement turns out to be a nightmare and he is forced to deal out his own brand of street corner justice.

Hooker and Gondorf pull a con on Macalinski, an especially nasty mob boss with the help of Veronica, a new grifter. They convince this new victim that Hooker is a somewhat dull boxer who is tired of taking dives for Gondorf. There is a ringer. Lonigan, their victim from the first movie, is setting them up to take the fall.
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