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Alexander Graham Bell falls in love with deaf girl Mabel Hubbard while teaching the deaf and trying to invent means for telegraphing the human voice. She urges him to put off thoughts of marriage until his experiments are complete. He invents the telephone, marries and becomes rich and famous, though his happiness is threatened when a rival company sets out to ruin him.

Physician Carole Nelson, suspected of having ties to notorious gangster Joe Gurney, must prove her innocence or the Medical Board will revoke her license. When Gurney seeks her out for treatment after being shot, it could be the break Nelson needs. Now she has a chance to use her medical know-how to outwit Gurney and his goons and reestablish her professional reputation.

When a confused eyewitness identifies New York City cabbie Brick Tennant as a killer, he is sentenced to death for a murder that he wasn't involved in. Though no one is willing to listen to the innocent prisoner's pleas for freedom, Brick's faithful fiancée, Mary, knows that her lover is innocent because she was with him when the crime was committed. As the scheduled execution draws ever nearer, Mary begins to investigate the murder herself.

Young Andy develops a crush on his drama teacher. When his play is chosen as the school's annual production, Andy seizes the opportunity to spend as much time as possible with his pretty teacher. Meanwhile, Judge Hardy has his own problems when he gets conned into forming a phony aluminum corporation.

Daniel Francis O'Toole, singing maestro in a New York restaurant, finds himself the unexpected heir to an estate in Ireland. He doesn't have money enough for the passage to Ireland, but the band members decide to incorporate him, advancing him the fare for equal shares in the estate. In Ireland, Danny finds that his is only a half-share, and the other half belongs to Mavourneen Kerrigan and she has the exclusive right to sell or keep the property...which, despite his pleas, she refuses to do. She also declares him an undesired guest, objects to his presence and insists that he prepare his own meals. He does so in a large main hall, but can only make hamburgers.

An elderly couple are forced to separate themselves from each other after their children refuse to take both into one house.

Complications ensue after a radio producer insults a sponsor.

A young man goes up against a crooked town boss.

Carny con artist and snake-oil salesman Eustace McGargle tries to stay one step ahead of the sheriff but is completely devoted to his beloved daughter Poppy.

In the 1840's Mexico has ceded California to the United States, making life nearly impossible for the Mexican population due to the influx of land and gold-crazy Americans. Farmer Joaquin Murrieta revenges the death of his wife against the four Americans who killed her and is branded an outlaw. The reward for his capture is increased as he subsequently kills the men who brutally murder his brother. Joining with bandit Three Fingered Jack, Murrieta raises an army of disaffected Mexicans and goes on a rampage against the Americans, finally forcing his erstwhile friend, Bill Warren, to lead a posse against him.
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