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In the year 2035, convict James Cole reluctantly volunteers to be sent back in time to discover the origin of a deadly virus that wiped out nearly all of the earth's population and forced the survivors into underground communities. But when Cole is mistakenly sent to 1990 instead of 1996, he's arrested and locked up in a mental hospital. There he meets psychiatrist Dr. Kathryn Railly and the son of a famous virus expert who may hold the key to the Army of the 12 Monkeys; thought to be responsible for unleashing the killer disease.

Leonard Shelby is tracking down the man who raped and murdered his wife. The difficulty of locating his wife's killer, however, is compounded by the fact that he suffers from a rare, untreatable form of short-term memory loss. Although he can recall details of life before his accident, Leonard cannot remember what happened fifteen minutes ago, where he's going, or why.

A solitary nurse bonds with a badly burned patient who survived an accident on an oil rig.

Young blonde translator Rebecca lives with her boyfriend ski instructor Marco in a mountain villa owned by her friend, nurse Laura. Rene, local cinema projectionist, steals Marco's car and gets into a car crash with local Theo, whose daughter, after being in coma for a time, dies. Rene suffers from partial short term memory loss and starts a relationship with Laura. Meanwhile Marco is looking for the man who stole his car and Theo - for the man who killed his daughter...

A young nurse, Alma, is put in charge of Elisabeth Vogler: an actress who is seemingly healthy in all respects, but will not talk. As they spend time together, Alma speaks to Elisabeth constantly, never receiving any answer.
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