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The secret US abduction of a suspected terrorist from his Middle East homeland leads to a wave of terrorist attacks in New York. An FBI senior agent and his team attempt to locate and decommission the enemy cells, but must also deal with an Army General gone rogue and a female CIA agent of uncertain loyalties.

Cynical bodyguard Jericho is hired by a man possessed by Satan, who is in search of his bride. When Jericho realizes what is happening, he must do everything he can to save the woman and the world.

Martin Brundle, born of the human/fly, is adopted by his father's place of employment (Bartok Inc.) while the employees simply wait for his mutant chromosomes to come out of their dormant state.

Following the public's realization that Thad Beaumont and George Stark are one and the same, the former stages a mock funeral, only for a series of gruesome murders to begin occurring as in his books.

Countless wiseguy films are spoofed in this film that centers on the neuroses and angst of a powerful Mafia racketeer who suffers from panic attacks. When Paul Vitti needs help dealing with his role in the "family," unlucky shrink Dr. Ben Sobel is given just days to resolve Vitti's emotional crisis and turn him into a happy, well-adjusted gangster.