Magister Negi Magi: Anime Final

Two years have passed since the final battle with Sephiroth. Though Midgar, city of mako, city of prosperity, has been reduced to ruins, its people slowly but steadily walk the road to reconstruction. However, a mysterious illness called Geostigma torments them. With no cure in sight, it brings death to the afflicted, one after another, robbing the people of their fledgling hope.

Following a brutal war, former soldier Van toils in a mine controlled by the ruling empire. One day, his solitary existence is upended when a pack of wild dogs carrying a deadly and incurable disease attack, leaving only Van and a young girl named Yuna as survivors. Finally free, the pair seek out a simple existence in the countryside but are pursued by nefarious forces. Intent on protecting Yuna at all costs, Van must uncover the true cause of the plague ravaging the kingdom—and its possible cure.

In 2061 CE, humanity's indiscriminate pollution of space has substantially hindered the development of space travel. In response, an international federation has designated the sun as a natural incinerator, federally establishing a treaty with the goal of first processing hazardous waste on Jupiter and forming the space environment defense force Cosmo Ecology. However, polluters evading surveillance networks continue to illegally dispose of radioactive waste directly into the sun. As a result, increased solar flare activity is on the verge of turning the Earth into a desert.

Six years ago a girl was found in the cellar with bite marks on her neck, and the villagers killed her. When one of the guests is killed and Miyuki is attacked by a creature with fangs, it would seem like the vampire is still there...

Datenshi-tachi no Kyōen is an OAV (1985) where the younger sister of a family (who gets in way over their heads) ends up owing the yakuza money. Because she can't pay, she is taken by the gang members to be used as a sexual toy. Then she vows to take gruesome revenge upon her perpetrators.